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WHAT IS CJC-1295 No DAC + Ipamorelin


The CJC-1295 + Ipamorelin combination — commonly called the “Gold Standard GH Stack” — is the most widely used growth hormone secretagogue stack for optimizing natural GH production. It pairs CJC-1295's ability to amplify GH pulse amplitude (as a GHRH analog) with Ipamorelin's clean, selective GH release (as a ghrelin mimetic) to produce a synergistic GH pulse significantly greater than either peptide alone.


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Why This Stack Works


CJC-1295 (no DAC): The Amplifier

  • GHRH receptor agonist: binds to GHRH receptors on pituitary somatotroph cells, stimulating them to produce and release growth hormone

  • Pulse amplitude: increases the amplitude (size) of each GH pulse without disrupting the natural pulsatile pattern

  • Short half-life (~30 min): the no-DAC form produces discrete GH pulses that mimic natural physiology, unlike the DAC version which creates sustained elevation

  • IGF-1 elevation: sustained use increases circulating IGF-1 levels, supporting tissue repair, muscle protein synthesis, and fat metabolism

Ipamorelin: The Clean Trigger

  • Ghrelin receptor agonist (GHRP): mimics the hunger hormone ghrelin to trigger GH release from a completely different receptor than CJC-1295

  • Selective GH release: unlike other GHRPs (GHRP-2, GHRP-6, Hexarelin), Ipamorelin does not significantly elevate cortisol or prolactin, making it the cleanest GHRP available

  • Dose-dependent response: produces a predictable, dose-dependent GH release with minimal desensitization over time

  • Mild hunger signaling: may slightly increase appetite through ghrelin mimicry, but far less than GHRP-6 or GHRP-2

Storage & Handling

Store at room temperature in the original packaging.
Protect from direct sunlight.
Keep away from moisture.
Keep the bottle tightly closed.

Shelf life under recommended conditions: up to the date indicated on the packaging (up to 24 months).

Store in a refrigerator at 2°C to 8°C.
Use within 28 days of reconstitution.
Protect from direct sunlight.
Do not freeze the solution.

Avoid temperature fluctuations.